The entire canticle reflects a thanksgiving liturgy in the Temple after recovery from an illness that threatened the psalmist's life.

In Christian liturgy this psalm is said in the Easter Vigil after the reading of Isaiah 54:5-14, which proclaims the consolation and rescue of Jerusalem after God had momentarily abandoned it.
In this context the psalm reveals its prophetic meaning, insofar as it proclaims what God did when he raised Jesus Christ after he had tasted death.

This psalm arrangement is also used in the following Masses:
•13th Sunday in Ordinary Time, Year B
•3rd Sunday of Easter, Year C
•10th Sunday in Ordinary Time, Year C